Principal Data Scientist – Optimization

Principal Data Scientist – Optimization is a role that will lead the development, validation, and deployment of advanced optimization models and decision-support solutions to guide strategic and operational decisions and help Amgen deliver on its “every patient, every time” mandate. This leader will partner across Commercial, Operations, Supply Chain, Manufacturing, Finance, and Technology to transform Amgen’s approach to operational decision making through rigorous analytical methods.

Requirements

• Design, build, and deploy optimization models using linear, nonlinear, and mixed-integer programming techniques to support high-value business decisions.
• Develop optimization solutions for challenging supply chain and commercial problems such as capacity allocation, supply planning, inventory optimization, portfolio tradeoffs, and price/margin optimization.
• Partner with forecasting, simulation, and analytics teams to incorporate uncertainty, demand scenarios, and operational variability into optimization-based decision frameworks.
• Own the end-to-end modeling lifecycle, including problem framing, prototype development, data analysis, model formulation, calibration, validation, testing, deployment, monitoring, and model explainability.
• Architect and develop decision-support tools and self-service applications that enable business leaders to evaluate tradeoffs and respond rapidly to changing market and operational conditions.
• Collaborate with cross-functional teams in Commercial, Operations, Finance, and Technology to ensure optimization solutions are integrated into critical business workflows and planning processes.
• Develop a holistic understanding of Amgen’s systems and processes in relation to industry challenges and broader trends to identify opportunities and risks.
• Evaluate emerging methods in optimization, reinforcement learning, and AI, and assess where they can complement classical operations research approaches.
• Establish optimization as a rigorous, scalable capability across the organization, while mentoring junior team members and setting standards for technical excellence.

Benefits

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental, and vision coverage, life, and disability insurance, and flexible spending accounts.
• Discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models, including remote and hybrid work arrangements, where possible.